The field of medicine is gradually embracing a paradigm shift from conventional approaches to targeted and individualised treatments that aim at improving the level of care to the patients. One such specific branch of precision medicine is precision biotherapeutics, which allows for the combination of diverse technologies, genomics, and data science approaches in coming up with very precise treatments. The outcome of these therapies is to resolve dysfunctions in treatment at the level of the patient’s genes, setting, and daily practice, which are more effective with fewer adverse effects. This essay looks at the emergence of precision biotherapeutics, the ways of operationalizing it, and why it must transform medicine.
Exact biological means of treatment having developed with the assistance of progression of these key technologies:

Genomics and Genetic Profiling: The introduction of next-generation sequencing (NGS) systems has normalized whole genome sequencing for patients in both cost and time perspective. This creates possibilities for looking into the diseases at the molecular level and analyzing mutations, genetic predispositions and pathways leading to the disease. In terms of oncology, for example, therapies may be directed towards oncogenes and tumor care genes, with each case of therapy being modified according to the genetic characteristics of the individual patient being treated.

CRISPR And Gene Editing: The application of CRISPR-Cas9 and other systems for genome engineering has made significant contributions towards more effective biotherapeutics. Such systems make it possible to delete a gene or insert a new, healthy one to teenagers afflicted with genetic diseases such as cystic fibrosis or muscular dystrophy.

RNA-based Therapeutics: Therapeutics developed on the basis of RNA technologies, including mRNA vaccines or RNA interference (RNAi), have emerged as potent weapons in the practice of precision medicine. Reprogrammed RNA can ceaselessly target and silence pre-recorded and post-transcriptional signals of injuries. The case of rapid creation and advancing of COVID-19 virus mRNA vaccines illustrates what RNA targeted treatment entails

Surabhi Rawat

University/College name : Upl university