Biotherapeutic medicines are important and essential component for modern medicine. The active ingredients of this medicine are derived from proteins and other substances produced by living organisms and are not like the usual kind of chemically synthesized small molecule medicine they are larger and more complex.

How are biotherapeutic medicines made?
In the world of growing population, new diseases are emerging due to this development of 1000s of medicines for each disease was discovered, but still some were incurable. The innovative treatment option for scientist were Biotherapeutic medicines. It harnesses the power of living organisms. These bacteria or cells do what they do naturally or modified to form protein or antibodies that are used for these medicines. They are designed for replacing the naturally missing protein. As biotherapeutic medicines cannot be made easily there are many tests undergone to create the right biotherapeutic medicine for that particular disease. The precision and conformance to scientific requirements are necessary for quality, safety and efficacy. Scientist should create the right environment for cells to isolate and purify the biotherapeutic protein every time.

Biotherapeutic medicines benefit many patients by treating prevalent diseases and rare illness. These medicines play an important role by diagnosing cancer and predicting the risk of cancer with the help of biomarkers. Biomarker is a biological molecule found in blood, other body fluids or tissues this is a sign of a normal or abnormal process, or of a condition or disease.

Biotherapeutic medicines has given success by treating autoimmune diseases as if left untreated autoimmune diseases it can lead to early mortality but now it has had a highly positive impact in the treatment of these diseases.

Examples: Xolair for asthma
Human Insulin for Diabetes mellitus
Anti-TNFs for Rheumatoid arthritis

Biotherapeutics in the field of conventional medicine can be divided into:
• Physical treatments, including surgery, radiotherapy
• Pharmacological treatments – encompassing the whole of conventional drug therapy

S. Rudhra Priya

University/College name : Sri Venkateswara College of Engineering, Sriperumbudur