Profile
Prof. Pulok Kumar Mukherjee is working as the Director; Institute of Bioresources and Sustainable Development (IBSD), Imphal. He has been working on chemical and therapeutic validation of natural products leading to drug discovery from Bio resources with its various translational components on Ethnopharmacology, chemical biology, Ethnobotany, metabolomics linked with chemistry of natural products, therapeutic validation, and related aspects. His has made outstanding contribution for evidence-based validation of herbs used in several ancient systems leading to discovery of drugs from nature and from the ancestors. He has made huge contribution on traditional medicine inspired drug discovery from Indian medicinal plants, Ethno pharmacology and evidence based validation of medicinal herbs to make them available from ‘Farm to Pharma’. His works on quality evaluation and validation of medicinal plants from Indian systems of medicine for the development of safe and quality phytopharmaceuticals has a great impact on the sustainable development of Bioeconomy.
Current Focus Areas
- Medicinal and Aromatic Plant research
- Phytopharmaceutical development
- Ethnopharmacology and Ethnomedicine
- Documentation of Traditional Knowledge
- Validation of traditional medicine
- Metabolomics for the development of Medicinal plants
- Bioeconomy from Bio resources
- Synergy Research
- Biosynthetic pathways for therapeutically important secondary metabolites
- Traditional medicine inspired Drug Development
- Bio-prospecting from bioresources
- Quality and safety evaluation of medicinal plants
- Network Pharmacology analysis in traditional medicines
- Entrepreneurship development
Selected Publications
Mukherjee PK, Das B, Bhardwaj PK, Tampha S, Singh HK, Demi Chanu L, Sharma N, Devi SI. Socio-economic sustainability with circular economy — An alternative approach The Science of The Total Environment (2023); 904(2):166630. DOI:10.1016/j.scitotenv.2023.166630
Banerjee S, Tiwari A, Kar A, Chanda J, Biswas S, Ulrich-Merzenich G, Mukherjee PK. Combining LC-MS/MS profiles with network pharmacology to predict molecular mechanisms of the hyperlipidemic activity of Lagenaria siceraria stand. J Ethnopharmacology (2023) 300:115633. doi: 10.1016/j.jep.2022.115633
Kar A, Mukherjee PK, Saha S, Banerjee S, Goswami D, Matsabisa MG, Charoensub R, Duangyod T. Metabolite profiling and evaluation of CYP450 interaction potential of ‘Trimada’- An Ayurvedic formulation. Journal of Ethnopharmacology (2020), 266:113457. doi: 10.1016/j.jep.2020.113457
Banerjee S, Bhattacharjee P, Kar A, Mukherjee PK. LC-MS/MS analysis and Network Pharmacology of Trigonella foenum-graecum- a plant from Ayurveda against Hyperlipidemia and Hyperglycemia with combination synergy. Phytomedicine, Elsevier (2019). 60:152944. doi: 10.1016/j.phymed.2019.152944
Chanda J, Mukherjee PK, Biswas R, Singha S, Kar A, Halder P K. Lagenaria siceraria and it's bioactive constituents in carbonic anhydrase inhibition: A bioactivity guided LC–MS/MS Approach. Phytochemical Analysis (2020), 2021; 32: 298–307. https://doi.org/10.1002/pca.2975