Profile
Working on single entity and multi-component bioactive natural products that may serve as leads for the development of new pharmaceuticals which may address therapeutic needs. In order to achieve the above goals, we are engaged in identification, isolation and purification of bioactive phyto-constituents from selected medicinal plants for further testing and subsequent use as either single entity pharmaceutical ingredient or component of standardized multi-component botanical products.
Current Focus Areas
Isolation and structure determination of organic products of medicinal significance from plants,studies on the structure , biochemistry and evaluation of biochemical effects of these active constituents for anti-inflammatory,anti-diabetics and anti-malaria.
Selected Publications
Chanu M. B., Chanu W. K., Singh B. K. (2024) GC-MS profiling, sub-acute toxicity study and total phenolic and flavonoid contentanalysis of methanolic leaf extract of Schima wallichii (D.C.) Korth- a traditional antidiabetic medicinal plant” Journal of Ethnopharmacology
Chanu W. K., Chatterjee A., Singh N., Nagaraj V. A., Singh B. K. (2024) Phytochemical investigations, antioxidant analyses, and in vitro and in vivo antimalarial activity of Rotheca serrata (Linn.) leaf extract and fractions. Journal of Ethnopharmacology, 321 117466
Chanu W. K., Chatterjee A., Singh N., Nagaraj V. A., Singh B. K. (2023) Antimalarial activity of Toona ciliata MJ Roem aqueous methanolic leaf extract and its antioxidant and phytochemical properties. Journal of Traditional and Complementary Medicine, 13(2023)550-560
Chanu W. K., Chatterjee A., Singh N., Nagaraj V. A., Singh B. K. (2022) Phytochemical screening, cytotoxicity assessment and evaluation of in vitro antiplasmodial and in vivo antimalarial activities of Mentha spicata L. methanolic leaf extract." Journal of Ethnopharmacology 298
Devi N. M., Nagarajan S., Singh B. K., Khongsai L., Chanu W. K., Wazzan M. A., Wazzan H., Abduljabbar A.H., Khan W., Khan A. (2023) Anti-oxidant, diabetic and inflammatory activities of Alpinia calcarata Roscoe extract. Chemistry & Biodiversity Journal