Profile
Dr. Girdhari Lal is a Senior Scientist working at the National Center for Cell Science (NCCS), Pune. Dr. Lal received Ph.D. in Immunology from Indian Institute of Science, Bangalore. He was an Assistant Professor at Mount Sinai School of Medicine, New York City, USA, before returning to India in the year 2010. Dr. Lal’s Laboratory is interested in understanding the cellular and molecular mechanism of immune tolerance. His laboratory is investigating the chemokine receptor signaling and neuroimmune communication in inflammation and autoimmunity. Dr. Lal Has received several National and International awards such as Ramalingaswami Fellowship and Innovative Young Biotechnologist Award from the Department of Biotechnology, and the Swarna Jayanti Fellowship from the Department of Science and Technology, Ministry of Science and Technology, Government of India. He is a founding member of Executing Council member of the Society of Inflammation Research and also Immuno-Oncology Society of India.
Current Focus Areas
We are investigating how neuroimmune communication affect the phenotype and function of immune cells in non-communicable diseases.
Selected Publications
Giri S, Metei HT, Mishra A, Lal G. (2022) Vγ2+ gamma-delta T cells in the presence of anti-CD40L control surgical inflammation and promote skin allografts survival. Journal of Investigative Dermatology. 142(10):2706-2714. PMID: 35378114.
Pathak M, Padghan P, Haldar N, Shilpi, Kulkarni N, Sonar, SA, Lal G. (2020) CCR9+ signaling in dendritic cells drives the differentiation of Foxp3+ Tregs and suppress the allergic IgE response in the gut. European Journal of Immunology 50:404-417. PMID 31755547
Paul S, Chhatar S, Mishra A, Lal G (2019) Natural killer T cell activation increases iNOS+CD206- M1 macrophage and controls the growth of solid tumor. Journal for Immunotherapy of Cancer. 7:208. PMID: 31387637
Kulkarni N, Meitei HT, Sonar SA, Sharma PK, Mujeeb, VR, Srivastava S, Boppana R, and Lal G (2018) CCR6 signaling inhibits suppressor function of induced-Treg during gut inflammation. Journal of Autoimmunity. 88:121-130. PMID 29126851.
Sonar SA, Meitei HT, Karmakar S, Mishra A, Inamdar S, Lenka N, Lal G (2024) Th17 cell promotes apoptosis of IL-23R+ neurons in experimental autoimmune encephalomyelitis. Clinical Immunology. 259:109898.. PMID 38185267