Profile
Ph.D. from Institute of Microbial Technology Chandigarh (IMTECH) - Characterised glutathione transporters of different yeasts Post-doc at National Institutes of Health – USA - Translation control of eukaryotic gene expression using yeast as a model system
Current Focus Areas
current focus is to probe the crucial role of protein translation process of pathogenic fungi to identify the novel therapeutic targets for the treatment of fungal diseases in humans.
Selected Publications
Biswas B, Rana A, Gupta N, Gupta I, Puria R and Thakur A* (2023). A novel robust method mimicking human substratum to dissect the heterogeneity of Candida auris biofilm formation. Microbiology Spectrum: Microbiol Spectr 2023 Jul 13;e0089223.doi: 10.1128/spectrum.00892-23
Biswas B, Gangwar G, Nain V, Gupta I, Thakur A* and Puria A* (2022) Rapamycin and Torin2 inhibit Candida auris TOR: Insights Through Growth profilling, docking and MD simulations. JBiomol Struct Dyn. 2022Oct 20;1-17
Rana A, Gupta N and Thakur A* (2021) Post-transcriptional and translational control of the morphology and virulence in human fungal pathogens. Molecular Aspects of medicines, Sep 5:101017. doi: 10.1016/j.mam.2021.101017
Anil Thakur A*, Gaikwad S, Vijjamarri A and Hinnebusch AG* (2020) eIF2α interactions with mRNA control accurate start codon selection by the translation preinitiation complex. Nucleic Acid research, 9;48(18):10280-10296.
Thakur A and Hinnebusch AG (2018) eIF1 Loop 2 interactions with Met-tRNAi control the accuracy of start codon selection by the scanning preinitiation complex. published in Proc Natl Acad Sci USA Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4159-E4168.