Profile
Basically ,Iam a Veterinarian with experience in breeding , Health of Laboratory animals including Genetically Modified animals ,Immunodeficient mouse models and Non huma Primates used for Research .Besides Intrest in development of animal models for Various diseases . Iam also Intrested i research on Hepatology and metabolic diseases with particular emphasis on NAFLD , HCC ,Obesity and Diabetes .
Current Focus Areas
Selected Publications
1. Kumar MM, Arindkar S, Saini M, Nagarajan P. Transcriptomic and pathological profiling of a new congenic mouse model with Lepr mutation: Evaluating susceptibility to the development of obesity and NAFLD. Genes & Diseases. 2023 Jun 21. 2. Singh, Parminder, et al. "Taurine deficiency as a driver of aging." Science 380.6649 (2023): eabn9257. 3. Sahu, P., Mohan, K. V., Aggarwal, S., Arindkar, S., Mahesh Kumar, J., Kumar Upadhyay, P., ... & Nagarajan, P. (2021). Apoptosis‐inducing factor deficient mice fail to develop hepatic steatosis under high fat high fructose diet or bile duct ligation. Cell Biochemistry and Function, 39(2), 296-307. 4. Mishra A, Das B, Nath M, Iyer S, Kesarwani A, Bhattacharjee J, Arindkar S, Sahay P, Jain K, Sahu P, Sinha P, Velpandian T, Nagarajan P, Upadhyay P A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration. Biol Open. 2017 Apr 15;6(4):449-462 5. Mishra A, Iyer S, Kesarwani A, Baligar P, Arya SP, Arindkar S, Kumar MJ, Upadhyay P, Majumdar SS, Nagarajan Perumal. Role of antigen presenting cell invariant chain in the development of hepatic steatosis in mouse model. Exp Cell Res. 2016 Jun 28