Profile

joined NII in 2007

Current Focus Areas

Selected Publications

  • Ibrar Siddique, Kajal Kamble, Sakshi Gupta, Kavita Solanki, Sumnil Bhola, Nuzhat Ahsan, Sarika Gupta * (2023). ARL6IP5 ameliorated synuclein burden by inducing autophagy via preventing ubiquitination and degradation of ATG12. Int. J. Mol. Sci. 24(13), 10499.

  • Prabhat Upadhyay, Diya Kalra, Aishwarya S. Nilakhe, Vijay Agrawal, Sarika Gupta* (2023). Polyherbal Formulation PL02 Alleviates Pain, Inflammation, and Subchondral Bone Deterioration in an Osteoarthritis Rodent Model. Front. Nutr. Sec. Nutrition and Metabolism, Volume 10 – 2023

  • Mayuri Khandelwal, Kapil Manglani, Prabhat Upadhyay, Mohammad Azad, Sarika Gupta* (2022) AdipoRon induces AMPK activation and ameliorates Alzheimer’s like pathologies and associated cognitive impairment in APP/PS1 mice. Neurobiology of Disease 174, 105876

  • Parminder Singh, Kishore Gollapalli, Stefano Mangiola, Daniela Schranner, Mohd Aslam Yusuf, Manish Chamoli, StingL.Shi, Bruno Lopes Bastos, Tripti Nair, Annett Riermeier, Elena M. Vayndorf, JudyZ.Wu, Aishwarya Nilakhe, ……., Sarika Gupta, Vidya Velagapudi, Anthony T. Papenfuss,Alaattin Kaya, Miguel Godinho Ferreir, Brian K. Kennedy, Julie K. Andersen,Gordon J. Lithgow, Abdullah Mahmood Ali, Arnab Mukhopadhyay, AarnoPalotie, Gabi Kastenmüller, Matt Kaeberlein, Henning Wackerhage, BhupinderPal, VijayK.Yadav* (2023). Taurine deficiency as a driver of aging. Science 380, eabn9257.

  • Gupta S*, Babu P, Surolia A*(2010). Biphenyl ethers conjugated CdSe/ZnS core/shell quantum dots and interpretation of the mechanism of amyloid fibril disruption. Biomaterials. Sep;31(26):6809-22.

Skills & Proficiency

ER-Stress Chronic Diseases neurodegenerative disease bone remodeling Drug design and development disease modifying therapy Brain Bone axis Alzheimer's disease ARL6IP5 Autophagy