Profile
I am a Statistician by training. My primary interest is in Human Genetics. I apply statistical and computational methods to infer about population migration, dispersal and diseases. My Masters and PhD is from Indian Statistical Institute. My post-doctoral training is at the Stanford University and University of California at San Francisco (UCSF). Currently, I am a Professor at the National Institute of BioMedical Genomics
Current Focus Areas
My research has two distinct components: theoretical method development and inferences from empirical evidence. My major focus has been population diversity and evolution with special emphasis on India.
My research interests include understanding complex genetic traits; ranging from skin pigmentation, possession of absolute pitch to cardiovascular diseases. I have worked extensively on methods and applications of admixture mapping.
My recent interests include analysis and dissection of archaic admixture in contemporary populations, high-throughput sequencing data analysis including AI-ML methods, finding genetic evidence of natural selection in populations and application of genetics in public health.
Selected Publications
BASU A, Mukherjee N, Roy S, Sengupta S, Banerjee S, Chakraborty M, Dey B, Roy M, Roy B, Bhattacharyya NP, Roychoudhury S, Majumder PP (2003) Ethnic India: a genomic view, with special reference to peopling and structure. Genome Research 13(10):2277-90
BASU A*, Sarkar-Roy N, Majumder PP (2016) Genomic reconstruction of the history of extant populations of India reveals five distinct ancestral components and a complex structure. Proc Natl Acad Sci U S A. Feb 9;113(6):1594-9.
Das S, Biswas N, BASU A* (2023) Mapinsights: deep exploration of quality issues and error profiles in high-throughput sequence data. Nucleic Acid Research 51:14 e75
Narang A, Jha P, Rawat V, Mukhopadhayay A, Dash D, BASU A*, Mukerji M (2011) Recent Admixture in an Indian Population of African Ancestry. American Journal of Human Genetics 89(1): 111 – 120.
BASU A, Tang H, Arnett D, Gu CC, Mosley TH, Kardia S, Luke A, Tayo B, Cooper R, Zhu X, Risch N (2009) Admixture Mapping of Quantitative Trait Loci for BMI in African Americans: Evidence for Loci on Chromosomes 3q, 5q and 15q. Obesity 17(6): 1226-31