Profile
Highly skilled Research Scientist with 17 years of post-Ph.D. experience specializing in stem cell biology and skeletal muscle biology in the context of nutrition and exercise. Adept in animal nutrition research, focusing on macronutrient and micronutrient regulation of insulin-sensitive tissues and development of stem cell differentiation protocols. Recipient of the Innovative Young Biotechnologist Award and grants from the Department of Biotechnology, India. Proficient in grant reviewing and scientific communication Demonstrated leadership in supervisory roles, including supervision of Ph.D students, and managing laboratory teams and implementing biorisk management protocols. Current projects are aimed at advancing our understanding of metabolic diseases as a consequence of skewed body composition
Current Focus Areas
Intergenerational effects of maternal skeletal muscle on offspring metabolism and role of myokines as signaling messengers
Selected Publications
6. Gopinath S.D*. (2017) Inhibition of STAT3 signaling ameliorates atrophy of the soleus muscles in mice lacking the vitamin D receptor Skeletal Muscle. (7) 2. doi: 10.1186/s13395-017-0121-2. 7. 2) Kumar, A., Kumar Y., Sevak, J., Kumar, S., Kumar., Gopinath S.D* (2020) Metabolomic analysis of primary human skeletal muscle cells during myogenic progression. Scientific Reports. 10(1184). doi.10.1038/s41598-020-68796-4 8. 3) Mishra, S., Sevak, J., Das, Anamica., Arimbasseri, A., Bhatnagar, S., Gopinath S.D*. (2020) Umbilical cord tissue is a robust source for mesenchymal stem cells with enhanced myogenic differentiation potential compared to cord blood. Scientific Reports. 10 (18978). doi.org/10.1038/s41598-020-75102-9 4) Das, Anamica., Gopinath S.D*., Arimbasseri, A*., (2021). A glycogen storage defect drives severe skeletal muscle atrophy in vitamin D receptor knockout mice. Journal of Cachexia, Sarcopenia and Muscle. DOI: 10.1002/jcsm.12841 5) Sevak, J & Gopinath S.D*., (2022). Generation of mesenchymal stem cells from human umbilical cord tissue and their differentiation into the skeletal muscle lineage. Journal of Visualized Experiments (JoVE). Doi: 10.3791/63725