Profile

Dr. Sharmila Bapat has assumed additional charge as Director, NCCS on 17 April 2024. She holds a Master’s degree in Microbiology and a PhD in Biochemistry, from the Pune University, and has been a faculty member at NCCS since January 2001. Recognized as a pioneer in cancer stem cell biology, her research aims towards understanding the cellular and molecular pathways underlying ovarian cancer to generate new knowledge and opportunities in precision cancer therapy. Besides several research publications she also has been granted a US patent and two Indian patents to her credit. Dr. Bapat is an elected Fellow of the National Academy of Sciences, India (Allahabad), the Indian Academy of Sciences (Bengaluru) and the Maharashtra Academy of Sciences. Her scientific achievements are recognized through several national and international awards and honors, most recent of which is the Shri RJ Kinarivala Cancer Research Award awarded by the Gujarat Cancer Society in 2023. She is also a recipient of a USIEF Fulbright Fellowship and Outreach Lecturing Fund (OLF) Award, TATA Innovation Fellowship Award from DBT, the R.M. Tiwari Research Oration Award, Prem Nath Wahi Award from ICMR, National Woman Bioscience Award from DBT, and a Group Award from The Cytometry Society, India.

Current Focus Areas

  • Biology of Cancer & Other Diseases

  • Chimerism in Biological Systems

Selected Publications

  • Shridhar A, More AS, Jadhav AR, Patil K, Mavlankar A, Dixit VM, Bapat SA. Comput Struct Biotechnol J. 2023; 21:5153-5164. doi: 10.1016/j.csbj.2023.10.028.

  • Shivalingappa PKM, Singh DK, Sharma V, Arora V, Shiras A, Bapat SA. RBM47 is an important regulator of mouse embryonic stem cell differentiation. Stem Cell Rev Rep. 2023 Feb;19(2):475-490. doi: 10.1007/s12015-022-10441-w. Epub 2022 Aug 20.

  • More MH, Varankar SS, Naik RR, Dhake RD, Ray P, Bankar RM, Mali AM, Subbalakshmi AR, Chakraborty P, Jolly MK, Bapat SA. A Multistep Tumor Growth Model of High Grade Serous Ovarian Carcinoma Identifies Hypoxia Associated Signatures. Cells Tissues Organs. 2022 Aug 15. doi: 10.1159/000526432. Online ahead of print.

  • Mishra P, Jadhav AR, Bapat SA. Single cell sequencing: A cutting edge tool in molecular medical research. Med J Armed Forces India. 2022 Sep;78(Suppl 1):S7-S13.

  • Varankar SS, Hari K, Bapat SA*, Jolly MK*. Cell Geometry Distinguishes Migration-Associated Heterogeneity in Two-Dimensional Systems. Comput Syst Oncol. 2022;2:e1041; * - co-communicating authors.

Skills & Proficiency

Cancer Biology Cancer Stem Cells Ovarian Cancer Biology Epithelial to Mesenchymal Transition (EMT) Tumor Heterogeneity Genome Architeture & Gene Regulation Chimerism in Biological Systems Novel Proteins & Neoantigens Pseudogenes