Profile
Dr Asif Mohmmed is a Group Leader and Principal Investigator at International Centre for Genetic Engineering and Biotechnology (ICGEB). Dr. Mohmmed, has received his PhD in Microbial Molecular Biology, and has been a research scientist at ICGEB for the past more than 20 years. He has been working in the field of infectious diseases for ~25 years.
Current Focus Areas
To understand cell biology of malaria parasite, specifically to characterize metabolic pathways unique for the malaria parasite.
Development of new antimalarial candidates.
Biomarker discovery for diagnosis and prognosis of pulmonary tuberculosis.
Selected Publications
Sheokand PK, Botté YY, Narwal M, Thakur V, Sebastien C, Islam MM, Banday MM, Asad M, Botté CY and Mohmmed A*. (2023) A Plasmodium falciparum lysophospholipase regulates host fatty acid chanelling through parasite lipid storage to enable controlled asexual schizogonic division, Cell Reports 42:112251.
Singh S., Datta G., Jain S., Thakur V., Arora P., Muneer A., Asad M., Ali S., and Mohmmed A.*. 2022. Dual role of an essential HtrA2/Omi protease in the human malaria parasite: maintenance of mitochondrial homeostasis and induction of apoptosis like cell death under cellular stress. PloS Pathogens 18(10):e1010932.
Kaul S., Nair V., Birla S., Dhawan S., Rathore S. , Khanna V., Lohiya S., Ali S., Mannan S., Rade K., Malhotra P., Gupta D., Khanna A., Mohmmed A.* (2022) Latent Tuberculosis Infection Diagnosis among Household Contacts in a High Tuberculosis-Burden Area: a Comparison between Transcript Signature and Interferon Gamma Release Assay, Microbiol Spectrum 10(2):e0244521.
Asad, M., Yamaryo-Botté, Y., Hossain, M.E., Thakur, V., Jain, S., Datta, G., Botté, C.Y., Mohmmed, A.* (2021). A lysophospholipase plays role in generation of neutral lipids required for hemozoin formation in malaria parasite. BMC Biology 19(1):159.
Rathore, S., Datta, G., Kaur, I., Malhotra, P., and Mohmmed A.* 2015. Disruption of cellular homeostasis induces organelle stress and triggers apoptosis like cell-death pathways in malaria parasite. Cell Death and Disease 6:e1803.