Profile
Dr Dhiraj Dhotre did his PhD under in NCCS, Pune. He worked as a project scientist from 2009 to 2019 at the National Centre for Microbial Resource, NCCS, Pune. He worked as a Senior Research Scientist in Reliance Life Science Pvt. Ltd. from 2019 before joining NCCS as Scientist D in July 2021. His research focus in last 14 years is in Human microbiome research. He has developed expertise in computational biology and genomics with a master’s degree in bioinformatics from the University of Pune. He has been working in the area of microbial genomics and metagenomics since 2009. He has focused on understanding the metabolic potential of microbes using genomic tools with either pathogenic or beneficial properties. He has developed software tools, web servers, and database management systems to cater to research in microbiology and human microbiome. He has seven national and international research grants and currently working as a PI from NCCS for the INSACOG (COVID genome consortium) project and Indian Human Microbiome Initiative. He published more than 60 research articles and 6 book chapters.
Current Focus Areas
Application of human microbiome in gut-brain axis, gastrointestinal and metabolic disorders
Development of software application for human microbiome research
Selected Publications
Spehlmann, Martina E; Rangrez, Ashraf Y; Dhotre, Dhiraj P; Schmiedel, Nesrin; Chavan, Nikita; Bang, Corinna; Müller, Oliver J; Shouche, Yogesh S; Franke, Andre; Frank, Derk, 2022. Heart Failure Severity Closely Correlates with Intestinal Dysbiosis and Subsequent Metabolomic Alterations. Biomedicines, 10 (809)
Mongad, Dattatray S; Chavan, Nikeeta S; Narwade, Nitin P; Dixit, Kunal; Shouche, Yogesh S; Dhotre, Dhiraj P; 2021, MicFunPred: A conserved approach to predict functional profiles from 16S rRNA gene sequence data. Genomics. 113, 3635-3643
Chaudhari, Diptaraj S; Dhotre, Dhiraj P; Agarwal, Dhiraj M; Gaike, Akshay H; Bhalerao, Devika; Jadhav, Parmeshwar,
DHOTRE, D. P., KUMBHARE, S. V, SINKAR, V. P., & SHOUCHE, Y. S. (2019). Human Gut Microbiome Research in India: A Retrospect and Future Opportunities. Proc Indian Natn Sci Acad, 85(4), 1051–1066.
Gaike, A. H., Paul, D., Bhute, S., Dhotre, D. P., Pande, P., Upadhyaya, S., Reddy, Y., Sampath, R., Ghosh, D., Chandraprabha, D., Acharya, J., Banerjee, G., Sinkar, V. P., Ghaskadbi, S. S., & Shouche, Y. S. (2020). The Gut Microbial Diversity of Newly Diagnosed Diabetics but Not of Prediabetics Is Significantly Different from That of Healthy Nondiabetics. MSystems, 5(2), e00578-19.