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Profile
I am Dr. Vikash K. Yadav, a Scientist at the National Institute of Plant Genome Research in New Delhi with a diverse academic background and extensive experience in plant biology. My lab's research interests focus on two main areas: Role of Higher-Order Chromatin Organization in Seed Biology: Investigating molecular mechanisms in seed development to enhance agricultural productivity. Employing epigenetic approaches and advanced sequencing techniques to identify enhancer elements governing gene expression related to seed vigor. Aim: Developing climate-ready crops for global food security. Dissecting Cell Heterogeneity in the Context of Epigenomics Landscape: Characterizing individual cell genomes to understand cellular diversity. Utilizing single-cell sequencing to create plant cell atlases based on epigenomic and transcriptomic data. Objective: Unraveling gene function at the single-cell level for comprehensive biological insights.
Current Focus Areas
Role of higher-order chromatin organization in seed biology.
Selected Publications
Yadav VK*, Jalmi SK, Tiwari S, Kerkar SK. (2023). Deciphering shared attributes of plant long non-coding RNAs through a comparative computational approach. Scientific Reports, 13, 15101.
Yadav VK* Sawant SV, Yadav A, Jalmi SK, Kerkar SK (2022). Genome-wide analysis of long non-coding RNAs under diel light exhibits role in floral development and the circadian clock in Arabidopsis thaliana. International Journal of Biological Macromolecules, 223, 1693-1704.
Yadav, V.K., Singh, S., Yadav A., Agarwal, N., Singh B., Jalmi, S.K., Yadav, V.K., Tiwari, V.K., Kumar, V., Singh, R and Sawant, S.V. (2021). Stress conditions modulate the chromatin interactions network in Arabidopsis. Frontiers in Genetics, 12:799805. doi: 10.3389/fgene.2021.799805.
Yadav, V.K., Santos-Gonzalez, J. and Kohler, C. (2021). INT-Hi-C reveals distinct chromatin architecture in endosperm and leaf tissues of Arabidopsis. Nucleic Acids Research, 49(8), 4371-4385.
Yadav V.K. and Claeys Bouuaert C. (2021). Mechanism and Control of Meiotic DNA Double-Strand Break Formation in S. cerevisiae. Frontiers in Cell and Developmental Biology, 9:642737. doi: 10.3389/fcell.2021.642737.