Abdul Jaleel K. A

Investigating the metabolic adaptations or alterations responsible for the onset of type 2 diabetes is the main theme of our laboratory. Insulin resistance is the hallmark of type 2 diabetes and one area our laboratory focuses is how independent risk factors for diabetes evolve over time in developing insulin resistance. Type 2 diabetes is a multi-factorial disease and have genetic, epigenetic and environmental components to its pathophysiology. The major objectives are addressed by performing human studies on a prospective cohort. Related to the laboratory theme, we also investigate molecular regulation in adepocyte biology, gene expression in dietary habits, and also metabolic alterations in subclinical deficiency of micronutrients.