Profile

2016 to 2018: Post-doctoral Associate , Bartolomucci Lab , University of Minnesota and Visiting fellow at University of California, Sandiego, U.S. Field of study: Functional characterization of neuroendocrine proteins and role in metabolic disease. 2013 to 2016: Research Associate, Margaret Robinson's Lab, Cambridge University, U.K. Field of study: Trafficking in Neurons and Neuroendocrine cells PhD 2007-2012: PhD under the supervision of Nitish R. Mahapatra, Department of Biotechnology, IIT-Madras, India.

Current Focus Areas

  • Cellbiology, neurodegeneration, Vesicular Trafficking, Drug development, Brain disease, Metabolic disorders.

Selected Publications

  • 1)Mukherjee M, Mukherjee C, Ghosh V, Jain A, Sadhukhan S, Dagar S, Sahu BS. Endoplasmic reticulum stress impedes regulated secretion by governing key exocytotic and granulogenic molecular switches. J Cell Sci. 2024 Mar 15;137(6):jcs261257. doi: 10.1242/jcs.261257. Epub 2024 Mar 19. (corresponding author)

  • 2)Garima Singh, Yuvaraju Venkataramaraju, Geetanjali Meher, Sahu BS, Mohammed Saleem, Yusuf Akhter, Distinct membrane perturbation effects of Catestatin and its CST-364 S variant: Insights from molecular simulations and anisotropy measurements, Biochimica et al. Biophysica Acta (BBA) - Biomembranes, Volume 1866, Issue 1,2024,184238, ISSN 0005-2736 (Joint Corresponding author)

  • 3)Sahu BS, Maria Razzoli, Seth McGonigle, Jean Pierre Pallais, Megin E. Nguyen, Masato Sadahiro, Cheng Jiang, Wei-Jye Lin, Kevin A. Kelley, Pedro Rodriguez, Rachel Mansk, Cheryl Cero, Giada Caviola, PaolaPalanza, Loredana Rao, Megan Beetch, Emilyn Alejandro, Yuk Y. Sham, Andrea Frontini, Stephen R. Salton, Alessandro Bartolomucci, Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis, Molecular Metabolism,2023,101781-ISSN 2212-8778.

  • 4)Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, Mahata SK, O`Grady S, McCorvy JD, Baier L, Sham YY, Bartolomucci. A. Peptide/receptor co-evolution explains the lipolytic function of the neuropeptide TLQP-21. Cell Reports. 2019; 28:2567–2580.

  • 5)Sahu BS *Ŧ, Sumana Mahata, Keya Bandyopadhyay, EnnioAvolio, Chinmayi Sahu, Gautam K. Bandyopadhyay, Alessandro Bartolomucci, Nicholas J.G. Webster, Angelo Corti, Lee Eiden, Sushil K. Mahata*. Catestatin regulates vesicular quanta by interacting with cholinergic and peptidergic stimulations in PC12 cells. Cell Tissue Res. 2019 Apr;376(1):51-70. (Co-corresponding Co-first author)

Skills & Proficiency

Biochemistry Cellbiology neurodegeneration Vesicular Trafficking Drug development Brain disease Metabolic disorders therapeutic neuropeptides neurochemistry molecular Biology