Profile
Scientist-C National Agri-Food Biotechnology Institute, Mohali till now Postdoctoral Fellow University of Liege, Belgium 2023-2024 Postdoctoral Fellow University of Tours, France 2022-2023 Research Associate, International Centre For Genetic Engineering And Biotechnology, Delhi 2021-2022 Ph.D. CSIR-Central Food Technological Research Institute (CFTRI), Mysore 2015-2020 M. Tech Biotechnology Gautam Buddha University, Greater Noida 2011-2014
Current Focus Areas
Strain engineering and biomanufacturing across various microorganisms. Our primary focus is on developing experiments aimed at enhancing strains performance and optimizing bioprocesses. This involves gene knock-outs, overexpression, heterologous expression and other techniques to boost the strain performance for biomolecule production.
Selected Publications
Bradley, S. A., Lehka, B. J., Hansson, F. G., Adhikari, K. B., Rago, D., Rubaszka, P., Haidar A., Chen., Hansen L., Gudich O., Giannakou K., Lengger B., Gill R., Nakamura Y., Bernonville T.D., Koudounas K., Romero-Suarez D., Ding L, Qiao Y, Frimurer T., Petersen A., Besseau S., Kumar S., Gautron N., Melin C., Marc J., Jeanneau R., O'Connor S., Courdavault V., Keasling J., & Jensen, M. K. (2023). Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast. Nature Chemical Biology, 19(12), 1551-1560. https://www.nature.com/articles/s41589-023-01430-2
Ogunyewo, O. A., Okereke, O. E., Kumar, S., & Yazdani, S. S. (2022). Characterization of a GH5 endoxylanase from Penicillium funiculosum and its synergism with GH16 endo-1, 3 (4)-glucanase in saccharification of sugarcane bagasse. Scientific Reports, 12(1), 17219. https://doi.org/10.1038/s41598-022-21529-1
Kumar, S., Tissopi T., Sadhu A., Mutturi, S. (2022) Surface display of novel transglycosylating α-glucosidase from Aspergillus neoniger on Pichia pastoris for synthesis of isomaltooligosaccharides. Biochemical Engineering Journal 181 (2022): 108400. https://doi.org/10.1016/j.bej.2022.108400
Kumar, S., Mutturi, S. (2021) Alternative splicing regulates the α-glucosidase synthesis in Aspergillus neoniger NCIM 1400. Fungal Biology, 125(8), 658-665. https://doi.org/10.1016/j.funbio.2021.04.001
Kumar, S., Mutturi, S. (2020). Expression of a novel α-glucosidase from Aspergillus neoniger in Pichia pastoris and its efficient recovery for synthesis of isomaltooligosaccharides. Enzyme and Microbial Technology. 141, 109653. https://doi.org/10.1016/j.enzmictec.2020.109653