Profile
Dr. Banerjee is a trained virologist with 12+ years of research experience in molecular virology, viral genetics, and pathogenesis. He did his M.Sc. in Biochemistry from the University of Calcutta and obtained his PhD from Jadavpur University in 2007. He was a postdoctoral fellow at Saint Louis University Center for Vaccine Development, Saint Louis, USA. In 2011, he joined the DBT-Translational Health Science and Technology Institute (THSTI) as a Research Scientist –D. In August 2018, he joined the Regional Centre for Biotechnology (RCB) in Faridabad. His research group at the RCB, Faridabad, is currently involved in deciphering the impact of viral infection on neutrophil phenotypes and function and how those phenotypically altered neutrophils are involved in disease outcomes. Dr Banerjee’s work is notable for using primary human cells and animal models to demonstrate immune-related mechanisms and illuminate potential avenues for therapeutic interventions. His team also develops small animal models to facilitate drug screening studies and immune responses against Dengue and Japanese Encephalitis viruses.
Current Focus Areas
Understanding the impact of Flavivirus infection on neutrophil biogenesis phenotypes and functions
Extracellular vesicles as a tool for understanding disease biology and novel intervention in viral infection
Harnessing multifaceted strategies targeting neutrophil exocytosis to reduce viral infection-induced inflammation
Selected Publications
Duggal S, Rawat S, Siddqui G, Vishwakarma P, Samal S, Banerjee A, Vrati S. Dengue Virus Infection In Mice Induces Bone Marrow Myeloid Cell Differentiation And Generates Ly6glow Immature Neutrophils With Modulated Functions. J Leukoc Biol. 2023 Aug 30:qiad099. doi: 10.1093/jleuko/qiad099. Online ahead of print. PMID: 37648666
Rawat S, Kumar S, Duggal S, Banerjee A. Phenotypic alteration by dengue virus serotype-2 delays neutrophil apoptosis and stimulates the release of prosurvival secretome with immunomodulatory functions. J Leukoc Biol. 2023 Oct 27:qiad133. doi: 10.1093/jleuko/qiad133. Online ahead of print.PMID: 37890093
1. Kumari S, Bandyopadhyay B, Singh A, Aggarwal S, Yadav AK, Vikram NK, Guchhait P, Banerjee A. Extracellular vesicles recovered from plasma of severe dengue patients induce CD4+ T cell suppression through PD-L1/PD-1 interaction. mBio. 2023 Nov 20:e0182323. doi: 10.1128/mbio.01823-23. Online ahead of print.PMID: 37982662
Soni N, Tripathi A, Mukherjee S, Gupta S, Mohanty S, Basu A, Banerjee A. Bone marrow-derived extracellular vesicles modulate the abundance of infiltrating immune cells in the brain and exert an antiviral effect against the Japanese Encephalitis virus. FASEB BioAdvances, 2022. doi: 10.1096/fba.2022-00071
Tripathi A, Shing B, Addya S, Surjit M, Kumar P, Vrati S, Banerjee A. Lack of Interferon 1 Regulatory Factor 8 Restricted IFN-gamma Response and Augmented Japanese Encephalitis Virus Replication in the Mouse Brain. J Virol. 2021 Oct 13;95(21):e0040621. doi:10.1128/JVI.00406-21.