Profile
Prasad did his M.Sc. (2003) from Andhra University, Vishakhapatnam, and Ph.D. (2011) from Osaka University, Japan. Then he worked as a postdoctoral fellow (2012-2016) at University of California Davis, U.S.A., under the Howard Hughes Medical Institute Investigator Neil Hunter. Later he continued as a post-doctoral research associate (2016-2017) at the same university. He Joined NIAB on 22nd January 2018.
Current Focus Areas
The focus of our laboratory is (a) the quality control pathways in oocyte and spermatocyte development to extend livestock fertility, (b) molecular mechanisms of meiotic processes in livestock to increase fecundity and prevent birth defects, (c) causes and treatments of ovarian disorders in livestock.
Selected Publications
Ajay. K . Singh et. al; Diminished NAD+ levels and activation of retrotransposons promote postovulatory aged oocyte (POAO) death; Cell Death Discov. 10, 104 (2024). https://doi.org/10.1038/s41420-024-01876-w
Lava Kumar. S$, Bhawna Kushawaha$, Aradhana Mohanty, Anjali Kumari, Ajith Kumar, Rohit Beniwal, Kiran Kumar. P, Mohd Athar, Krishna Rao. D, and H.B.D. Prasada Rao*; Glutathione peroxidase (GPX1) - Selenocysteine metabolism preserves the Follicular Fluid's (FF) redox homeostasis via IGF-1- NMD cascade in Follicular ovarian Cysts (FOCs). Biochimica et Biophysica Acta (BBA)- Molecular Basis of Disease. 12 May 2024, 167235.
S. Lava Kumar, Aradhana Mohanty, Anjali Kumari, Ajith Kumar. E, Ranjit Kumar. S, Mohd Athar, Kiran Kumar P, Rohit Beniwal, Moukthika M. Potula, Gandham R. K., and H.B.D. Prasada Rao*: Balanced spatiotemporal arrangements of histone H3 and H4 posttranslational modifications are necessary for meiotic prophase I chromosome organization; Journal of Cellular Physiology. 10.1002/jcp.31201; 2024.
Ajay K Singh, S. Lava Kumar, Rohit Beniwal, Aradhana Mohanty, Bhawana Kushwaha, and H.B.D. Prasada Rao*. Local DNA synthesis is critical for oocyte DNA repair during maturation.; Journal of cell science.257774. doi: 10.1242/jcs.257774; 2021.
H.B.D. Prasada Rao, Huanyu Qiao, Shubhang K. Bhatt, Logan R.J. Bailey, Hung D. Tran, Sarah L. Bourne, Wendy Qiu, Anusha Deshpande, Ajay N. Sharma, Connor J. Beebout, Roberto J. Pezza and Neil Hunter (2017). A SUMO-Ubiquitin Relay Recruits Proteasomes to Chromosome Axes to Regulate Meiotic Recombination. Science, 27Jan 2017: Vol. 355, Issue 6323, pp. 403-407.