Profile
Dr. Amol Suryawanshi is an eminent scientist extensively working in area on Clinical proteomics more than 15 years. He has completed his graduation and post-graduation in veterinary sciences from Mumbai veterinary college, Mumbai. He received his Ph.D. from ICMR-National Institute for Research in Reproductive Health, Mumbai. His lab works in area of Clinical Proteomics with major focus to understand variations in cellular proteome due to various biological/disease conditions using high throughput mass spectrometry- based proteomics approaches and decipher their significance/role in cellular physiology and disease pathogenesis. His overall goal is Disease Proteome Mapping, Bio-marker discovery in various clinical diseases, decipher the role of important protein/s in disease pathogenesis, and Post-transnational modification/s (PTMs) and their role in diseases At present, focus is on the diseases such as cancers (Nasopharyngeal Carcinoma, Cervical / ovarian cancer) and viral diseases (Rabies, COVID-19, Chikungunya, Dengue).
Current Focus Areas
Clinical Proteomics: Understanding of cancer and viral diseases through clinical proteomics
Disease Proteome Mapping to understand biology or Disease Pathogenesis
Bio-marker discovery in various clinical diseases
To decipher the role of important protein/s in disease pathogenesis
Post-transnational modification/s (PTMs) and their role in disease pathogenesis
Selected Publications
Behera S, Reddy RR, Taunk K, Rapole S, Pharande RR, Suryawanshi AR. Delineation of altered brain proteins associated with furious rabies virus infection in dogs by quantitative proteomics. J Proteomics. 2022 Feb 20;253:104463. doi: 10.1016/j.jprot.2021.104463.
Behera S., Pharande R. R., Reddy R. R., Majee S. B., Mukherjee S., and Suryawanshi A. R.*. (2020). Quantitative proteomics leads to identify dog brain proteins involved in rabies virus infection: Implication in understanding viral pathophysiology. Journal of proteins and proteomics 11, 241–257. https://doi.org/10.1007/s42485-020-00051-w
Suresh V, Mohanty V, Avula K, Ghosh A, Singh B, Reddy RK, Parida D, Suryawanshi AR, Raghav SK, Chattopadhyay S, Prasad P, Swain RK, Dash R, Parida A, Syed GH, Senapati S. (2021). Quantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host factors having implication in the disease pathogenesis and severity. FASEB J. Jul;35(7):e21713. doi: 10.1096/fj.202100431R.
Ghosh, S., Kundu, R., Chandana, M., Das, R., Anand, A., Beura, S., Bobde, R. C., Jain, V., Prabhu, S. R., Behera, P. K., Mohanty, A. K., Chakrapani, M., Satyamoorthy, K., Suryawanshi, A. R., Dixit, A., Padmanaban, G., & Nagaraj, V. A. (2023). Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement. Nature communications, 14(1), 4216. https://doi.org/10.1038/s41467-023-39670-4
Singh B, Avula K, Chatterjee S, Datey A, Ghosh A, De S, Keshry SS, Ghosh S, Suryawanshi AR, Dash R, Senapati S, Beuria TK, Prasad P, Raghav S, Swain R, Parida A, Hussain Syed G, Chattopadhyay S. Isolation and Characterization of Five Severe Acute Respiratory Syndrome Coronavirus 2 Strains of Different Clades and Lineages Circulating in Eastern India. Front Microbiol. 2022 Jun 30;13:856913. doi: 10.3389/fmicb.2022.856913.