Profile
Dr. Ellora Sen obtained her Ph.D. in Immunology from the Indian Institute of Chemical Biology CSIR-IICB. Her post-doctoral research was at Department of Microbiology & Immunology, Pennsylvania State University, USA, and later at the Department of Neurology and Neurosciences, Rutgers University, USA. She joined the National Brain Research Centre as Principal Investigator in 2006. She also holds a Master degree in Philosophy from IGNOU
Current Focus Areas
Understanding how genetic/epigenetic landscape in gliomas with different molecular signatures having prognostic values, influences chemoresistance and immune surveillance.
Selected Publications
Lathoria K, Gowda P, Umdor SB, Patrick S, Suri V, Sen E (2023). PRMT1 driven PTX3 regulates ferritinophagy in glioma. Autophagy, DOI: 10.1080/ 1554862.2023. 2165757. Cover Page
Patrick S, Gowda P, Lathoria K, Suri V, Sen E (2021). Diminished YAP1 affects mitochondrial dynamics in IDH1 mutant glioma. Journal of Cell Science, 134(22): jcs259188.
Gowda P, Lathoria K, Sharma S, Patrick S, Umdor SB, Sen E (2021). Rewiring of lactate-IL-1β auto-regulatory loop with Clock-Bmal1: A feed-forward circuit in glioma. Molecular and Cellular Biology, 41(9):e0044920.
Gowda P, Patrick S, Singh A, Sheikh T and Sen E (2018). Mutant IDH1 disrupts PKM2-b-catenin-BRG1 transcriptional network driven CD47 expression. Molecular and Cellular Biology, 38: (9):e00001-18
Sheikh T, Gupta P, Gowda P, Patrick S and Sen E (2018). Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells. The Journal of Biological Chemistry, 93(13):4767-4777