Profile
Dr Nitin Kumar Singhal holds a Master's degree from IIT Roorkee and a PhD in Bioinorganic Chemistry from IIT Bombay, completed under the mentorship of Prof. C. P. Rao in 2008. His dissertation, titled "Glyco-conjugates based on Ribose, Galactose, & Lactose: Synthesis, Characterization, Metal Ion Recognition, Complexation, & Binding & altering the Properties of Some Lectins & Glycosidases," showcases his expertise in glyco-conjugates and their interactions with metal ions. Dr.Singhal further specialized in nanobioscience with a postdoctoral fellowship at Seoul National University, South Korea. Member of National Academy of Sciences and a Fulbright Fellow, he is currently developing biosensor device using aptamer and glycoconjugate receptors to detect foodborne bacteria. His research group also focuses on creating ginger-based exosome nanoformulations for managing T2DM and formulating strategies to ameliorate iron deficiency anemia. Our aim to enhance food safety, provide natural therapeutic options for diabetes, and improve iron absorption and health outcomes.
Current Focus Areas
Current research focuses on developing biosensors for detecting foodborne bacteria, creating ginger-based exosome nanoformulations for type 2 diabetes management, and formulating strategies to ameliorate iron deficiency anemia. These innovations aim to enhance food safety, provide natural therapeutic options for diabetes, and improve iron absorption and health outcomes.
Selected Publications
1. Garg, P., Priyadarshi, N., Ambule, M.D., Kaur, G., Kaul, S., Gupta, R., Sagar, P., Bajaj, G., Yadav, B., Rishi, V. and Goyal, B. Multiepitope glycan-based laser assisted fluorescent nanocomposite with dual functionality for sensing and ablation of Pseudomonas aeruginosa (2023) Nanoscale, 15, 37,.15179-15195. 2. Ritika Gupta, Vishal Singh, Nikita Sarawagi, Gurmeet Kaur, Raminder Kaur, Nitesh Priyadarshi, Vikas Rishi, Bhupesh Goyal, Padmaja P Mishra, Nitin K Singhal. Salmonella typhimurium detection and ablation using OmpD specific aptamer with non-magnetic and magnetic graphene oxide (2023), Biosensors and Bioelectronics, 234, 115354. 3. Priyadarshi, Nitesh, Mayur D. Ambule, Shimayali Kaushal, Asheesh Kumar, Poonam Sagar, Ajay Kumar Srivastava, and Nitin Kumar Singhal. "Nanoglycocluster based diagnostic platform for colorimetric detection of bacteria; A comparative study analysing the effect of AuNPs size, linker length, and glycan diversity." Biosensors and Bioelectronics (2022): 113969. 4. Vishal Singh, Poonam Sagar, Sunaina Kaul, Rajat Sandhir, Nitin Kumar Singhal (2021) Liver Phosphoenolpyruvate Carboxykinase-1 Downregulation via siRNA-Functionalized Graphene Oxide Nanosheets Restores Glucose Homeostasis in a Type 2 Diabetes Mellitus In Vivo Model Bioconjugate Chemistry 32(2), 259. 5. Sagar, Poonam, Vishal Singh, Ritika Gupta, Sunaina Kaul, Shikha Sharma, Simranjit Kaur, Rupam Kumar Bhunia, Kanthi Kiran Kondepudi, and Nitin Kumar Singhal. "pH-Triggered, Synbiotic Hydrogel Beads for In Vivo Therapy of Iron Deficiency Anemia and Reduced Inflammatory Response." ACS Applied Bio Materials 4, no. 10 (2021): 7467-7484.