Profile
Dr. Neeti Sanan-Mishra is the Group leader of Plant RNAi Biology at ICGEB, New Delhi. She has made significant contributions in the field of plant biotechnology by investigating the miRNA networks involved in regulating plant development in response to virus infection and abiotic stresses. The research in her group is directed towards understanding the RNAi mechanisms operative in plants in response to high temperature, drought, salt stress and virus infection. Their endeavour is to use this knowledge to develop a new approach for crop improvement and protection in the era of global climate change. Her group is working on miRNAs that play a key role under multiple environmental stresses to regulate the metabolic circuits related to grain yield. They are interested in utilizing miRNAs as tools for improving plant adaptation and sustaining yields.
Current Focus Areas
They have identified miRNAs that are co-modulated in response to salinity and high temperature stress (HTS) in rice and are responsible for integrating stress responses with light regulated development. They are specifically looking at the miRNAs that regulating plant response to thermopriming and HTS.
Selected Publications
Sanan-Mishra N, Tripathi A, Goswami K, Shukla RN, Vasudevan M, Goswami H. ARMOUR - A Rice miRNA: mRNA Interaction Resource. Front Plant Sci. 2018 May 8;9:602. doi: 10.3389/fpls.2018.00602. PMID: 29868062; PMCID: PMC5952065.
Kushawaha AK, Khan A, Sopory SK, Sanan-Mishra N. Priming by High Temperature Stress Induces MicroRNA Regulated Heat Shock Modules Indicating Their Involvement in Thermopriming Response in Rice. Life (Basel). 2021 Mar 29;11(4):291. doi: 10.3390/life11040291. PMID: 33805566; PMCID: PMC8067039. Copy
Goel S, Goswami K, Pandey VK, Pandey M, Sanan-Mishra N. Identification of microRNA-target modules from rice variety Pusa Basmati-1 under high temperature and salt stress. Funct Integr Genomics. 2019 Nov;19(6):867-888. doi: 10.1007/s10142-019-00673-4. Epub 2019 May 24. PMID: 31127449.