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Profile
Dr. Jutur's primary focus of research is understanding the dynamics of microalgal systems through an integrative multi-omics approach in coherence with reconstructed genome-scale metabolic models (GEMs) with well-defined functional pathways that will elucidate an effective strategy for converting light/carbon source to biomass, biofuels and biorenewables (B3) for sustainable futuristic solutions. Our findings will provide important breakthroughs on central metabolism in these microalgae, which are required for biotechnological improvement of next-generation biofuel production.
Current Focus Areas
Omics integration for bioactive compound discovery in microalgae, addressing fragmented data sources and standardized tools. Multidisciplinary research accelerates biofuel and biorenewable compound discovery from microalgae.
Implementing two-stage cultivation and genetic engineering to enhance microalgae's adaptiveness and lipid/carotenoid production. Innovating omics technologies for oxidative stress responses furthers biofuel and bioproduct production, with a focus on scalability and techno-economic feasibility.
Leveraging solar energy for carbon capture and isoprenoid production, emphasizing scalability, mutant development, and multiproduct applications. Efficient extraction and recycling ensure long-term sustainability, supported by carbon sequestration and environmental benefits.
Transcriptional engineering manipulates microalgae metabolism for high-value bioproducts, extending beyond fatty acids to isoprenoids and carotenoids. Synthetic cis-elements and CRISPR-Cas9 facilitate precise compound production, enhancing microalgae's industrial potential.
Investigating molecular mechanisms of light energy conversion to enhance microalgae biomass, biofuels and biorenewables. Overcoming efficiency challenges through biotechnological engineering promises significant advancements in sustainable energy production from microalgae.
Selected Publications
Sawant, K.R., Sarnaik, A.P., Singh, R., Savvashe, P., Baier, T., Kruse, O., Jutur, P.P., Lali, A., and Pandit, R.A. (2024). Outdoor cultivation and metabolomics exploration of Chlamydomonas engineered for bisabolene production. Bioresource Technology 398, 130513. https://doi.org/10.1016/j.biortech.2024.130513 [IF: 11.889]
Sharma, J., Mariam, I., Kareya, M.S., Jutur, P. P., Joshi, M., Harish, Bhatnagar, A., Chaurasia, A.K. and Nigam, S. Metabolomic response of microalgae towards diclofenac sodium during its removal from water and concomitant recovery of pigments and lipids. Bioresource Technology, 371: 128617, 2023. doi: 10.1016/j.biortech.2023.128617 [IF: 11.889].
Paliwal, C., and P. P. Jutur. Dynamic allocation of carbon flux triggered by task-specific chemicals is an effective non-gene disruptive strategy for sustainable and cost-effective algal biorefineries. Chemical Engineering Journal, 418: 129413, 2021. doi: 10.1016/j.cej.2021.129413 [IF: 16.744]
Shaikh, K.M., Kumar, P., Nesamma, A. A., Abdin, M.Z., and P.P. Jutur. Hybrid genome assembly and functional annotation reveals insights on lipid biosynthesis of oleaginous native isolate Parachlorella kessleri, a potential industrial strain for production of biofuel precursors. Algal Research, 52: 102118, 2020. doi: 10.1016/j.algal.2020.102118 [IF: 5.276]
Shaikh, K. M., Nesamma, A. A., Abdin, M.Z., and P.P. Jutur. Molecular profiling of an oleaginous trebouxiophycean Alga Parachlorella kessleri subjected to nutrient deprivation for enhanced biofuel production. Biotechnology for Biofuels, 12: 182, 2019. doi: 10.1186/s13068-019-1521-9 [IF: 7.67]