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Profile
I received a B.Sc. from the University of Delhi, Delhi, and M.Sc (Biotechnology) from Allahabad University, Allahabad, India. I did a Ph.D. from Jawaharlal University (JNU), working at ICGEB, New Delhi, India. He then worked at Institut Pasteur, Paris (2008-2011) and Institut National de Transfusion Sanguine, Paris (2011-2012) as a Post-doctoral Fellow. I joined the National Institute of Animal Biotechnology (NIAB) in 2013. Presently I am working as a Scientist E at NIAB.
Current Focus Areas
Ticks: They are obligate haematophagous ectoparasites of wild and domestic animals as well as humans. They are the second largest arthropod vectors for transmitting diseases. We are working towards (a) New plant based acaricides, (b) Understanding proteins in salivary glands, (c) Field sampling for disease load in ticks.
Theileriosis: It is caused by the apicomplexan parasite Theileria. This is a unique parasite as it causes unchecked proliferation of the leucocytes We are working towards (a) identifying newer targets for development of vaccine and new drug molecules, (b) understanding of parasite factors involved in transformation of the host cells.
Immunology of ruminants: B cells are important for basic and translational research. In the case of ruminants, the information about the subclasses of B cells is very limited. A precise identification and phenotypic characterization of ruminants’ is required. We are developing monoclonal antibodies against various CD markers of bovine/ovine.
Mastitis: It is one of the biggest problem in the dairy industry. We have recently started work on various hypothetical proteins associated with biofilm formation in the bovine.
Selected Publications
Araveti PB, Kar PP, Kuriakose A, Sanju A, Kumar KA, Srivastava A*. Identification of a novel interaction between Theileria Prohibitin (TaPHB-1) and bovine RUVBL-1. Microbiology Spectrum. Volume 11, Number 1, 14 February 2023.
.Kar, P.P., Araveti, P.B., Kuriakose, A. Srivastava A*. Design of a multi-epitope protein as a subunit vaccine against lumpy skin disease using an immunoinformatics approach. Sci Rep 12, 19411 (2022)
Kar PP, Araveti PB, Srivastava A*. Deciphering the kinome of Theileria annulata for identification of drug targets and anti-theilerial drug. Ticks Tick Borne Dis. 2022 Sep 29;13(6):102049.
Araveti PB, Kar PP, Kuriakose A, Sanju A, Kumar KA, Srivastava A*. Identification of a novel interaction between Theileria Prohibitin (TaPHB-1) and bovine RUVBL-1. Microbiology Spectrum. Volume 11, Number 1, 14 February 2023.
Araveti PB, Vijay M, Kar PP, Varunan S, Srivastava A*. MMV560185 from Pathogen box induces extrinsic pathway of apoptosis in Theileria annulata infected bovine leucocytes International Journal for Parasitology: Drugs and Drug Resistance Volume 18, April 2022, Pages 20-31
Araveti, P.B., Srivastava, A*. Curcumin induced oxidative stress causes autophagy and apoptosis in bovine leucocytes transformed by Theileria annulata. Cell Death Discov. 5, 100 (2019).