The integration of therapeutic nutrition into clinical care holds promise for enhancing patient outcomes, especially for those with neurological disorders, tuberculosis, cancer and malnutrition. At the Himalayan Institute of Medical Sciences (HIMS), a leading tertiary care hospital in Uttarakhand, the need for specialized nutritional interventions has become increasingly evident. Given the potential of diet-based therapies like the ketogenic diet in managing neurological disorders, the critical role of supportive nutrition during tuberculosis, cancer treatment, special foods focused on developing ready-to-use therapeutic diets (RUTDs) tailored for pregnant and lactating women, and children, a Biomanufacturing hub can be established at Swami Rama Himalayan University (SRHU). This facility will address the immediate needs of our patient population and contribute to advancing clinical nutrition research and innovation.
The ketogenic diet, a high-fat, low-carbohydrate regimen, has shown significant therapeutic potential in managing various neurological conditions, including epilepsy, Alzheimer’s disease (AD), and depression. Studies have shown that this diet can reduce seizure frequency in epilepsy patients, improve cognitive function in Alzheimer’s patients, and modulate mood disorders. Despite its benefits, access to fresh ketogenic food remains a challenge for many patients, particularly those with rare neurological disorders. This often necessitates costly procurement, making it financially unfeasible for long-term use.
Nutritional needs can vary significantly among cancer patients depending on the type and stage of cancer, the treatments being undertaken, and individual health profiles. Customizing dietary strategies to cater to specific types of cancer can help optimize patient outcomes by managing symptoms, enhancing recovery, and supporting overall well-being. Diets high in lean protein sources (tofu, legumes) are essential to support muscle mass and immune function, particularly during chemotherapy. Additionally, incorporating foods rich in phytonutrients, such as cruciferous vegetables (broccoli, kale, Brussels sprouts) and berries, can help combat inflammation and reduce oxidative stress, which is critical for breast cancer patients.
Food for special dietary needs (FSDN) designed for children under five years of age can offer a vital intervention by providing energy-dense foods that are rich in proteins, essential vitamins, and minerals to address common deficiencies.
One of the major risk factors of high TB incidents in developing countries like India is
malnutrition or undernutrition which is directly linked to the low immunity of the population
in the region. In India, undernutrition is also linked with a higher risk of developing active
TB in household contacts of TB patients and drug-resistant TB patients which poses serious
repercussions in controlling TB transmission and achieving the goal of a TB-free India. A
rich diet of proteins, fats, and micronutrients (minerals and vitamins) with high calories was
considered crucial for TB patients before the introduction of antituberculosis therapy. Food insecurity in the close contacts/household contacts of TB patients increases the risk of disease development and progression in India.
Additionally, biomanufacturing hub will serve as an innovation platform for regional entrepreneurs and researchers. By offering access to state-of-the-art facilities, individuals with novel ideas in therapeutic nutrition can test and scale their products, fostering a vibrant innovation ecosystem. This facility will support the incubation of new ventures and contributing to the broader community’s health and economic well-being.

Smita Dimri

University/College name : Swami Rama Himalayan University